Pharmacology case study; Chapter 3, Toxic Effects of Drugs; A nurse is caring for a patient taking an antibiotic that was shown to be effective for the microorganism in culture and sensitivity test. The patient information sheet that accompanied the drug tells the patient to observe for adverse drug reactions. (Learning Objectives 1, 2, and 3). What is an adverse drugs reaction, and what is the clinical significance of this reaction?The drug may have other effects on the body besides the therapeutic effect.
Pharmacology case study; The patient is sensitive to the drug being given. The drug’s action on the body causes other responses that are undesirable or unpleasant.
Pharmacology case study; The patient is taking too much or too little of the drugs, leading to negative effects. Some adverse effects can be countered with specific comfort measures or precautions. Knowing that these effects may occur and what actions can be taken to prevent or cope with them may be the most critical factor in helping the patient to comply with drug therapy.
Pharmacology case study; What are the four types of allergic reactions and assessments to drug treatment that could occur with antibiotic drug administration? Anaphylactic reaction: It involves an antibody that reacts with specific sites in the body to cause the release of chemicals, including histamine that produces immediate reactions that can lead to respiratory distress and even cessation of breathing .
Pharmacology case study; Key assessments are hives, rash, difficulty breathing, increased blood pressure, dilated pupils, diaphoresis, “panic” feeling, increased heart rate, and/or respiratory arrest. Cytotoxic reaction: It involves antibodies that circulate in the blood and attack antigens on cell sites, causing death of that cell. This reaction is not immediate but may be seen over a few days.
Pharmacology case study; Assessments include complete blood count showing damage to blood-forming cells (decreased hematocrit, white blood cell count, and platelets), liver function tests showing elevated liver enzymes, and/or renal function test showing decreased renal performance . Pharmacology case study;